ea0077p50 | Metabolism, Obesity and Diabetes | SFEBES2021
Parenti Cristina
, Lad Nikita
, Williams C Neil
, Sharpe Graham R
, Nelson Carl P
, Murphy Alice M
, McTernan Philip G
Background: Lipocalin 2 (NGAL) is considered a pro-inflammatory adipokine. Noting the conflicting reports as to the role of Lipocalin 2 in metabolic disease, it remains unclear whether an acute or chronic state affects its impact on adipocyte function. In an attempt to address this our current studies investigated for the first time in humans, whether Lipocalin 2 in abdominal subcutaneous adipose tissue (AT) may influence mitochondrial function and browning of adipocytes, as c...